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CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction.
Yang D, Cho H, Tayyebi Z, Shukla A, Luo R, Dixon G, Ursu V, Stransky S, Tremmel DM, Sackett SD, Koche R, Kaplan SJ, Li QV, Park J, Zhu Z, Rosen BP, Pulecio J, Shi ZD, Bram Y, Schwartz RE, Odorico JS, Sidoli S, Wright CV, Leslie CS, Huangfu D. Yang D, et al. Among authors: kaplan sj. Nat Cell Biol. 2022 Jul;24(7):1064-1076. doi: 10.1038/s41556-022-00946-4. Epub 2022 Jul 4. Nat Cell Biol. 2022. PMID: 35787684 Free PMC article.
Genetic Engineering of Immune Evasive Stem Cell-Derived Islets.
Sackett SD, Kaplan SJ, Mitchell SA, Brown ME, Burrack AL, Grey S, Huangfu D, Odorico J. Sackett SD, et al. Among authors: kaplan sj. Transpl Int. 2022 Dec 5;35:10817. doi: 10.3389/ti.2022.10817. eCollection 2022. Transpl Int. 2022. PMID: 36545154 Free PMC article. Review.
Epigenetic Reprogramming Strategies to Reverse Global Loss of 5-Hydroxymethylcytosine, a Prognostic Factor for Poor Survival in High-grade Serous Ovarian Cancer.
Tucker DW, Getchell CR, McCarthy ET, Ohman AW, Sasamoto N, Xu S, Ko JY, Gupta M, Shafrir A, Medina JE, Lee JJ, MacDonald LA, Malik A, Hasselblatt KT, Li W, Zhang H, Kaplan SJ, Murphy GF, Hirsch MS, Liu JF, Matulonis UA, Terry KL, Lian CG, Dinulescu DM. Tucker DW, et al. Among authors: kaplan sj. Clin Cancer Res. 2018 Mar 15;24(6):1389-1401. doi: 10.1158/1078-0432.CCR-17-1958. Epub 2017 Dec 20. Clin Cancer Res. 2018. PMID: 29263182 Free PMC article.